Description

Pyrazine, 2-(Bromomethyl)-5-Methyl- is a versatile brominated pyrazine derivative, a key building block in advanced organic synthesis. Its reactive bromomethyl group makes it an essential intermediate for constructing complex heterocyclic systems and functionalized molecules. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used to develop advanced fungicides, herbicides, and insecticides by incorporating the pyrazine core into active molecules.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers and light-emitting components.
• Flavor and Fragrance Chemistry: Acts as a key intermediate for synthesizing complex pyrazine-based aroma compounds used in high-value flavor formulations.
• Chemical Biology Probes: Utilized to create tagged molecules and activity-based probes for studying biological pathways and enzyme functions.

Basic Information

Item	Detail
Product Name	Pyrazine, 2-(Bromomethyl)-5-Methyl-
CAS No.	79068-46-5
Molecular Formula	C6H7BrN2
Molecular Weight	187.04 g/mol
Synonyms	2-(Bromomethyl)-5-methylpyrazine; 5-Methyl-2-(bromomethyl)pyrazine; 2-Bromomethyl-5-methylpyrazine; (5-Methylpyrazin-2-yl)methyl bromide; 5-Methyl-2-pyrazinemethyl bromide; Methyl 5-methylpyrazine-2-carboxylate (precursor related); 2,5-Disubstituted Pyrazine Bromide
EINECS	Contact for details

Quality Control

Every batch of Pyrazine, 2-(Bromomethyl)-5-Methyl- is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure product integrity and traceability for your regulatory filings. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.