Description

5,12,20-Trihydroxy-6,8,10,14-Eicosatetraenoic Acid is a specialized polyhydroxylated fatty acid derivative, also known as a lipoxin analog, which plays a significant role in cellular signaling and inflammatory response modulation. This compound is valued for its high purity and structural specificity, making it a critical reference standard and research chemical in advanced biochemical studies. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on immunology, inflammation resolution pathways, and the development of novel therapeutic agents.

Application

• Biochemical Research: Serves as a key reference standard and analytical standard in lipidomics and eicosanoid research.
• Pharmaceutical Development: Used as an intermediate or lead compound in the research of novel anti-inflammatory and pro-resolving therapeutics.
• Cell Signaling Studies: Applied in vitro and in vivo to study lipoxin-mediated pathways, inflammation resolution, and immune system modulation.
• Academic Research: A vital tool for universities and research institutes investigating the biochemistry of specialized pro-resolving mediators (SPMs).
• Diagnostic Reagent Manufacturing: Potential use in the development of high-sensitivity assay kits for detecting inflammatory biomarkers.

Basic Information

Product Name	5,12,20-Trihydroxy-6,8,10,14-Eicosatetraenoic Acid
CAS No.	79008-24-5
Molecular Formula	C₂₀H₃₂O₅
Molecular Weight	352.47 g/mol
Synonyms	5(S),12(S),20-Trihydroxy-6(E),8(E),10(E),14(Z)-eicosatetraenoic acid; Lipoxin A4 analog; LXA4 analog; 5,12,20-TriHETE; (5S,6E,8E,10E,12S,14Z)-5,12,20-Trihydroxyicosa-6,8,10,14-tetraenoic acid; Trihydroxyeicosatetraenoic acid
EINECS	Contact for details

Quality Control

Our 5,12,20-Trihydroxy-6,8,10,14-Eicosatetraenoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with stated specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 1.0%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.