Description

Mofezolac CAS NO 78967-07-4 is a non-steroidal anti-inflammatory drug (NSAID) belonging to the oxicam class, functioning as a potent and selective cyclooxygenase (COX) inhibitor. Its primary value lies in providing effective analgesic and anti-inflammatory action with a well-characterized pharmacological profile for research and development. This compound is essential for pharmaceutical R&D laboratories, academic institutions, and manufacturers focused on developing novel therapeutic agents, studying inflammation pathways, or producing reference standards.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for quality control and analytical method development in drug manufacturing.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key synthetic building block in the production of finished dosage forms for pain and inflammation management.
• Biomedical Research: Employed in in vitro and in vivo studies to investigate COX enzyme inhibition mechanisms, pharmacokinetics, and efficacy models.
• Analytical Testing: Utilized as an analytical standard in HPLC, LC-MS, and NMR for assay validation, impurity profiling, and stability studies.
• Preclinical Development: Applied in formulation studies and toxicology assessments during the drug discovery pipeline.

Basic Information

Product Name	Mofezolac
CAS No.	78967-07-4
Molecular Formula	C₁₇H₁₄N₂O₄
Molecular Weight	310.31 g/mol
Synonyms	Mofezolac; AC-576; (±)-Mofezolac; 4-(3,5-Diphenyl-1H-pyrazol-1-yl)benzenesulfonamide; 1-[4-(Aminosulfonyl)phenyl]-3,5-diphenyl-1H-pyrazole; AC 576; AC576; CCRIS 6655; HSDB 7725; Mofezolacum
EINECS	Contact for details

Quality Control

Our Mofezolac is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and NMR to ensure it meets stringent specifications. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.