Description

1-o-Hexadecyl-2-o-Ethyl-Sn-Glycero-3-Phosphorylcholine is a synthetic, single-isomer phospholipid analog, a key building block in advanced lipid research and formulation. This high-purity compound is critical for creating precisely defined model membranes and liposomal delivery systems with controlled surface properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for applications requiring specific membrane fluidity, charge, and stability characteristics.

Application

• Liposomal Drug Delivery Systems: As a structural component to engineer liposomes with tailored stability, release profiles, and targeting capabilities.
• Biomimetic Membrane Research: For constructing defined model membranes (e.g., vesicles, supported lipid bilayers) to study membrane protein interactions, permeability, and fusion processes.
• Pharmaceutical Excipient Development: Used in the research and development of novel lipid-based excipients for enhancing drug solubility and bioavailability.
• Diagnostic Reagents: As a component in the formulation of lipid-based reagents for diagnostic assays and imaging.
• Cosmetic & Dermal Formulations: Incorporated into advanced cosmetic products for its biomimetic properties and potential to improve skin barrier function and active ingredient delivery.
• Biophysical Studies: Essential for calorimetry, spectroscopy, and microscopy studies investigating lipid-lipid and lipid-protein interactions.

Basic Information

Product Name	1-o-Hexadecyl-2-o-Ethyl-Sn-Glycero-3-Phosphorylcholine
CAS No.	78858-42-1
Molecular Formula	C26H55NO6P
Molecular Weight	508.70 g/mol
Synonyms	1-Hexadecyl-2-ethyl-sn-glycero-3-phosphocholine; 1-O-Hexadecyl-2-O-ethyl-sn-glycero-3-phosphocholine; C16-Ethyl-PC; ET-16-O-PC; 2-Ethyl-PAF; Platelet-Activating Factor C16 Analog; sn-1-C16:0-alkyl-sn-2-C2:0-alkyl-glycerophosphocholine; Hexadecyl Ethyl Phosphatidylcholine
EINECS	Contact for details

Quality Control

Our 1-o-Hexadecyl-2-o-Ethyl-Sn-Glycero-3-Phosphorylcholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and isomer confirmation, NMR for structural verification, and mass spectrometry. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its sensitivity to oxidation and moisture. For long-term storage, desiccate. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid/wax
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (sn-1)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.