Description

16-Iodohexadecanoic Acid is a high-purity, long-chain iodinated fatty acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of the iodine atom, which acts as an excellent leaving group for subsequent functionalization via cross-coupling reactions like Suzuki or Negishi couplings. This compound is essential for researchers and manufacturers in pharmaceutical development, lipidomics research, and the creation of specialty surfactants and polymer precursors.

Application

• Pharmaceutical Intermediate: Key synthon for creating novel drug candidates, particularly in metabolic disease and oncology research.
• Bioconjugation & Probe Synthesis: Used to introduce fatty acid chains into biomolecules (peptides, proteins) for labeling, tracking, or modifying biological activity.
• Lipidomics Standard: Serves as a reference standard or internal standard in mass spectrometry for analyzing complex lipid mixtures.
• Polymer Chemistry: Monomer for synthesizing functionalized polymers with tailored surface properties.
• Surface-Active Agent Precursor: Intermediate in the production of specialized iodinated or functionalized surfactants.
• Material Science Research: Building block for self-assembled monolayers (SAMs) and organic thin films.
• Chemical Biology Tool: Employed to study protein lipidation and membrane interactions.

Basic Information

Item	Details
Product Name	16-Iodohexadecanoic Acid
CAS No.	78774-43-3
Molecular Formula	C₁₆H₃₁IO₂
Molecular Weight	382.33 g/mol
Synonyms	16-Iodopalmitic Acid; ω-Iodohexadecanoic Acid; Hexadecanoic Acid, 16-iodo-; Palmitic Acid, 16-iodo-; 16-Iodo-1-pentadecanecarboxylic Acid; Iodopalmitic Acid; 16-Iodocetylic Acid
EINECS	Contact for details

Quality Control

Every batch of 16-Iodohexadecanoic Acid is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency. Our standard grade typically meets a purity specification of ≥95% (by HPLC), suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We can support development projects requiring custom specifications or compliance with cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.