Description

(2R, 4'R, 8'S)-α-Tocopherol CAS NO 78656-12-9 is a specific, high-purity stereoisomer of natural vitamin E, distinguished by its defined (2R, 4'R, 8'S) configuration. This compound matters because it offers superior biological activity and stability compared to synthetic mixtures, making it the preferred choice for high-performance applications. It is critically needed by manufacturers in the pharmaceutical, nutraceutical, and premium cosmetic industries seeking the highest quality and efficacy for their formulations.

Application

• Pharmaceutical Formulations: As an active pharmaceutical ingredient (API) in prescription and over-the-counter products for vitamin E supplementation.
• Nutraceuticals & Dietary Supplements: A key ingredient in high-potency capsules, softgels, and liquid formulations for antioxidant support.
• Premium Cosmetics & Skincare: Used in anti-aging serums, creams, and lotions for its skin-protective and moisturizing properties.
• Functional Foods & Beverages: Fortification of foods and drinks to enhance nutritional value and shelf-life stability.
• Animal Nutrition: An essential nutrient in high-grade feed premixes for livestock, poultry, and pets.
• Biochemical Research: As a reference standard and reagent in life science research and analytical laboratories.

Basic Information

Product Name	(2R, 4'R, 8'S)-α-Tocopherol
CAS No.	78656-12-9
Molecular Formula	C29H50O2
Molecular Weight	430.71 g/mol
Synonyms	d-α-Tocopherol; RRR-α-Tocopherol; Natural Vitamin E; (R,R,R)-α-Tocopherol; 2R,4'R,8'R-α-Tocopherol; 2R,4'R,8'R-α-Tocopherol; Vitamin E (natural form); 5,7,8-Trimethyltocol; EINECS 278-769-9
EINECS	278-769-9

Quality Control

Our (2R, 4'R, 8'S)-α-Tocopherol is manufactured under strict quality management systems. Each batch is tested to meet or exceed relevant pharmacopeial standards such as USP/NF and EP. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to ensure traceability and compliance for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) at a controlled room temperature of 15-25°C (59-77°F) to minimize oxidation. Keep the container tightly sealed in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Clear, pale yellow to yellow viscous oil
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 96.0%
Specific Rotation	+0.20° to +0.30° (at 20°C)
Heavy Metals	≤ 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.