Description

1-Benzyl-2(S)-Isobutyl-Piperazine is a chiral piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a crucial chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with specific stereochemical configurations.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Employed as a chiral ligand or auxiliary in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Research: Used in the synthesis of advanced, stereochemically-defined pesticides and herbicides.
• Fine Chemical Production: Serves as a precursor for complex molecules used in material science and specialty polymers.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	1-Benzyl-2(S)-Isobutyl-Piperazine
CAS No.	78551-90-3
Molecular Formula	C15H24N2
Molecular Weight	232.37 g/mol
Synonyms	(S)-1-Benzyl-2-(2-methylpropyl)piperazine; (S)-1-Benzyl-2-isobutylpiperazine; 2(S)-Isobutyl-1-benzylpiperazine; 1-Benzyl-2-[(2S)-2-methylpropyl]piperazine; Benzyl-(S)-isobutylpiperazine; (S)-(-)-1-Benzyl-2-isobutylpiperazine; (S)-1-Benzyl-2-isobutyl-piperazine; 78551-90-3
EINECS	Contact for details

Quality Control

Our 1-Benzyl-2(S)-Isobutyl-Piperazine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) providing purity, enantiomeric excess (ee), and impurity profile is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.