Description

4-Benzyl-3-Oxopiperazine-1-Carboxylic Acid tert-Butyl Ester CAS NO 78551-60-7 is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring a reliable, high-quality intermediate for constructing complex pharmaceutical molecules. It is primarily utilized in the development of active pharmaceutical ingredients (APIs) and novel chemical entities within the life sciences sector.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Peptidomimetic Research: Used to construct constrained peptide analogs and protease inhibitor scaffolds due to its piperazine core.
• Medicinal Chemistry: Serves as a versatile building block for structure-activity relationship (SAR) studies and lead optimization programs.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke, multi-step synthetic routes.
• Chemical Biology: Useful for creating molecular probes and tool compounds to study biological pathways.
• Agrochemical Development: Potential intermediate in the synthesis of novel crop protection agents.

Basic Information

Product Name	4-Benzyl-3-Oxopiperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	78551-60-7
Molecular Formula	C₁₆H₂₂N₂O₃
Molecular Weight	290.36 g/mol
Synonyms	tert-Butyl 4-benzyl-3-oxopiperazine-1-carboxylate; 1-Boc-4-benzyl-2,3-dioxopiperazine; 1-(tert-Butoxycarbonyl)-4-benzyl-2,3-dioxopiperazine; 4-Benzyl-2,3-dioxo-1-piperazinecarboxylic Acid 1,1-Dimethylethyl Ester; 4-Benzyl-3-oxo-1-piperazinecarboxylic acid tert-butyl ester; 1-N-Boc-4-benzyl-2,3-diketopiperazine; BOC-DKP(Bzl); 78551-60-7
EINECS	Contact for details

Quality Control

Our 4-Benzyl-3-Oxopiperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and a Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.