Description

1-Benzylpiperazin-2-One Hydrochloride is a high-purity organic salt compound with significant utility in advanced chemical synthesis. This material serves as a critical building block and intermediate for the development of complex molecules, particularly within the pharmaceutical research and development sector. It is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs) and other fine chemicals. The compound's defined structure and purity are paramount for ensuring reproducible results in sensitive synthetic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) guidelines.
• Biochemical Tool Compound: May be utilized in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Fine Chemical Synthesis: Serves as a versatile intermediate for the production of specialty chemicals, agrochemicals, and other complex organic molecules.

Basic Information

Product Name	1-Benzylpiperazin-2-One Hydrochloride
CAS No.	78551-58-3
Molecular Formula	C11H15ClN2O
Molecular Weight	226.70 g/mol
Synonyms	1-Benzyl-2-piperazinone hydrochloride; 1-Benzylpiperazin-2-one HCl; 2(1H)-Piperazinone, 1-benzyl-, hydrochloride; Benzylpiperazinone hydrochloride; 1-Benzyl-1,4-diazepan-2-one hydrochloride; 1-Benzyl-2-ketopiperazine hydrochloride; 2-Oxo-1-benzylpiperazine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Benzylpiperazin-2-One Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via techniques such as HPLC, NMR, and IR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.