Description

(S)-3-Methyl-2-Ketopiperazine CAS NO 78551-38-9 is a high-purity, chiral piperazine derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs), particularly for chiral drugs targeting the central nervous system. Pharmaceutical R&D teams and fine chemical manufacturers need it to create novel therapeutic agents with high stereochemical purity and efficacy.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel APIs, especially in neurological and psychiatric drug discovery.
• Asymmetric Synthesis: Used as a starting material or catalyst ligand in stereoselective reactions to construct complex molecular architectures.
• Protease Inhibitor Research: Serves as a core scaffold in the development of inhibitors for various enzymatic targets.
• Agrochemical Development: Employed in the research and synthesis of advanced, chiral agrochemicals with specific biological activity.
• Academic & Contract Research: A valuable reagent for universities and CROs conducting research in medicinal chemistry and synthetic methodology.
• Peptidomimetics: Used in the design and synthesis of peptide analogs with improved metabolic stability and bioavailability.

Basic Information

Product Name	(S)-3-Methyl-2-Ketopiperazine
CAS No.	78551-38-9
Molecular Formula	C5H10N2O
Molecular Weight	114.15 g/mol
Synonyms	(S)-3-Methylpiperazine-2-one; (3S)-3-Methyl-2-piperazinone; (S)-3-Methyl-2-oxopiperazine; (S)-3-Methylpiperazin-2-one; (S)-3-Methyl-2,3-dihydropyrazin-2(1H)-one; (S)-3-Methyl-1,4-diazinan-2-one; (S)-3-Methyl-2-ketopiperazine; (S)-3-Methyl-2-piperazinone
EINECS	Contact for details

Quality Control

Our (S)-3-Methyl-2-Ketopiperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.