Description

1,3-Propanediol, 2-(1-Piperazinyl)- is a specialized organic compound that serves as a versatile building block in advanced chemical synthesis. Its unique structure, combining a diol with a piperazine moiety, makes it a valuable intermediate for creating complex molecules with specific functionalities. This product is essential for research and development chemists and manufacturers in the pharmaceutical and fine chemical industries, where it is used to develop active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological or receptor-based therapies.
• Ligand and Chelator Synthesis: Used in the development of complexing agents and ligands for catalysis or metal ion sequestration.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce piperazine groups into polymer backbones, altering material properties.
• Bioconjugation Chemistry: Serves as a spacer or linker molecule in the development of antibody-drug conjugates (ADCs) or diagnostic probes.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex heterocyclic compounds and specialty chemicals.
• Research & Development: A valuable tool in medicinal chemistry and chemical biology for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	1,3-Propanediol, 2-(1-Piperazinyl)-
CAS No.	78531-48-3
Molecular Formula	C7H16N2O2
Molecular Weight	160.22 g/mol
Synonyms	2-(Piperazin-1-yl)propane-1,3-diol; 1,3-Propanediol, 2-(1-piperazinyl)-; 2-(1-Piperazinyl)-1,3-propanediol; 1,3-Propanediol, 2-piperazinyl-; NSC 169046; 2-Piperazin-1-ylpropane-1,3-diol; Piperazine, 1-(2,3-dihydroxypropyl)-
EINECS	Contact for details

Quality Control

Our production of 1,3-Propanediol, 2-(1-Piperazinyl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supported by a detailed Certificate of Analysis (COA). We are committed to meeting the exacting standards required for pharmaceutical R&D and GMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.