Description

2-Amino-3,7-dimethylimidazo[4,5-f]quinoxaline is a heterocyclic aromatic amine of significant interest in advanced chemical research and development. This compound serves as a critical building block and reference standard in the study of mutagenic and carcinogenic substances. It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical developers focused on food safety, toxicology, and metabolic pathway analysis. Its well-defined structure makes it essential for calibration, method validation, and investigative studies.

Application

• Analytical Reference Standard: Used as a high-purity calibrant in HPLC, LC-MS, and GC-MS for the quantification of heterocyclic aromatic amines (HAAs) in complex matrices.
• Toxicological Research: Serves as a model compound in studies investigating the mutagenicity, genotoxicity, and metabolic activation pathways of cooked food-derived contaminants.
• Food Safety & Quality Control: Employed by testing laboratories to develop and validate analytical methods for monitoring HAA levels in processed meat, fish, and other protein-rich foods.
• Biomedical Research: Utilized in biochemical research to understand DNA adduct formation and the mechanisms of chemical carcinogenesis.
• Pharmaceutical Impurity Profiling: Acts as a potential impurity reference standard in the synthesis and quality control of related pharmaceutical compounds.
• Academic & Institutional Research: Provides a key reagent for universities and research institutes conducting studies in organic chemistry, environmental chemistry, and public health.

Basic Information

Product Name	2-Amino-3,7-dimethylimidazo[4,5-f]quinoxaline
CAS No.	78411-56-0
Molecular Formula	C12H11N5
Molecular Weight	225.25 g/mol
Synonyms	2-Amino-3,7-dimethylimidazo(4,5-f)quinoxaline; 3,7-Dimethyl-2-aminoimidazo[4,5-f]quinoxaline; 2-Amino-3,7-DiMeIQx; MeIQx (specific isomer); 2-Amino-3,7-dimethyl-3H-imidazo[4,5-f]quinoxaline; Heterocyclic Aromatic Amine (HAA) Standard; CAS 78411-56-0
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3,7-dimethylimidazo[4,5-f]quinoxaline is produced and analyzed under strict quality management protocols. We employ advanced chromatographic techniques to ensure high purity and batch-to-batch consistency, critical for research and analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and should be handled to minimize prolonged exposure to air and moisture.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95% (Research Grade)
Purity (HPLC)	≥ 98% (Analytical Standard Grade)
Water Content (KF)	< 1.0%
Residue on Ignition	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.