Description

(2S)-(+)-2,5-Dihydro-3,6-Dimethoxy-2-Isopropylpyrazine is a high-purity chiral intermediate and flavoring agent with a characteristic nutty, roasted aroma. Its value lies in its role as a key building block for synthesizing more complex molecules and as a potent flavor enhancer in the food industry. This compound is essential for manufacturers in the pharmaceutical, flavor & fragrance, and fine chemical sectors seeking reliable, high-quality intermediates for research and production. CAS No. 78342-42-4.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring specific stereochemistry.
• Flavor & Fragrance Industry: Used as a potent flavoring agent to impart roasted, nutty, and popcorn-like notes to food products, savory flavors, and snack seasonings.
• Fine Chemical Synthesis: Acts as a versatile building block in organic synthesis for creating heterocyclic compounds and complex molecular architectures.
• Research & Development: Employed in academic and industrial R&D for method development and exploring new synthetic pathways involving pyrazine derivatives.
• Food Technology: Enhances the flavor profile of processed foods, meat analogs, and ready-to-eat meals where authentic roasted flavors are desired.

Basic Information

Product Name	(2S)-(+)-2,5-Dihydro-3,6-Dimethoxy-2-Isopropylpyrazine
CAS No.	78342-42-4
Molecular Formula	C9H16N2O2
Molecular Weight	184.24 g/mol
Synonyms	(S)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine; (2S)-2,5-Dihydro-3,6-dimethoxy-2-(1-methylethyl)pyrazine; L-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine; (+)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine; FEMA 4239; 2-Isopropyl-3,6-dimethoxy-2H-pyrazine; Roasty pyrazine; Nutty pyrazine
EINECS	Contact for details

Quality Control

Our (2S)-(+)-2,5-Dihydro-3,6-Dimethoxy-2-Isopropylpyrazine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical and food-grade applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific rotation is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Specific Rotation [α]20/D	+50° to +60° (c=1 in CHCl3)
Refractive Index n20/D	1.470 - 1.480
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.