Description

Tetramethylpyrazine is a high-purity heterocyclic compound, also known as Ligustrazine, valued for its distinct nutty, roasted aroma and significant biological activity. This versatile chemical serves as a key flavoring agent and a valuable pharmaceutical intermediate. It is essential for manufacturers in the flavor & fragrance, pharmaceutical, and nutraceutical industries seeking reliable, high-quality raw materials.

Application

• Flavor & Fragrance Industry: Used as a key aroma compound to impart roasted, nutty, and cocoa-like notes to food products, beverages, and savory flavorings.
• Pharmaceutical Synthesis: Acts as a crucial intermediate (Ligustrazine) in the production of cardiovascular and cerebrovascular drugs due to its vasodilatory and anti-platelet aggregation properties.
• Nutraceuticals & Dietary Supplements: Incorporated into health supplements for its potential antioxidant and circulation-supporting benefits.
• Chemical Research: Serves as a standard or building block in organic synthesis and biochemical research for developing new compounds.
• Food Processing: Enhances the flavor profile of processed foods, including snacks, baked goods, and meat analogs.

Basic Information

Product Name	Tetramethylpyrazine
CAS No.	1124-11-4
Molecular Formula	C8H12N2
Molecular Weight	136.20 g/mol
Synonyms	2,3,5,6-Tetramethylpyrazine; Ligustrazine; TMP; Tetramethyl-1,4-diazine; Pyrazine, tetramethyl-; FEMA 3237; Flavor and Extract Manufacturers' Association 3237
EINECS	214-391-5

Quality Control

Our Tetramethylpyrazine is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity. We can supply grades suitable for flavor, pharmaceutical intermediate, and research applications, with specifications aligning with industry standards such as FCC (Food Chemicals Codex) where applicable. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	74 - 78 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.