Description

Dimethyl Pyrazine-2,5-Dicarboxylate is a high-purity diester derivative of pyrazine-2,5-dicarboxylic acid, serving as a versatile and critical building block in advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex heterocyclic molecules, pharmaceuticals, and functional materials. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for synthesizing active ingredients and sophisticated intermediates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those containing pyrazine or pyridine-like heterocyclic cores for antiviral, anticancer, or central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the pyrazine moiety contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating chelating ligands used in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, metal-organic frameworks (MOFs), and other functional polymers due to its rigid, planar structure and ester functionalities.
• Flavor and Fragrance Industry: Acts as an intermediate for synthesizing specific pyrazine-based aroma compounds, though typically requiring further chemical transformation.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and for creating libraries of compounds for high-throughput screening.

Basic Information

Product Name	Dimethyl Pyrazine-2,5-Dicarboxylate
CAS No.	13051-89-3
Molecular Formula	C8H8N2O4
Molecular Weight	196.16 g/mol
Synonyms	2,5-Pyrazinedicarboxylic Acid Dimethyl Ester; Dimethyl 2,5-Pyrazinedicarboxylate; Pyrazine-2,5-dicarboxylic Acid Dimethyl Ester; Methyl Pyrazine-2,5-dicarboxylate; 2,5-Dimethoxycarbonylpyrazine; Dimethyl 1,4-Diazine-2,5-dicarboxylate; NSC 404087; 2,5-Bis(methoxycarbonyl)pyrazine
EINECS	Contact for details

Quality Control

Our Dimethyl Pyrazine-2,5-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.