Description

Diclofenac Diethylamine CAS NO 78213-16-8 is a non-steroidal anti-inflammatory drug (NSAID) salt, specifically the diethylamine salt of diclofenac. This compound is a critical active pharmaceutical ingredient (API) intermediate, valued for its enhanced solubility and bioavailability compared to the free acid form. It is primarily required by pharmaceutical manufacturers for the production of topical analgesic and anti-inflammatory formulations, such as gels, creams, and patches, targeting pain and inflammation management.

Application

• Topical Analgesic Gels and Creams: Primary use as the active ingredient in formulations for the relief of muscle, joint, and localized pain.
• Transdermal Patches: Used in controlled-release patch systems for sustained pain management.
• Anti-inflammatory Ointments: Key component in topical products designed to reduce swelling and inflammation associated with arthritis and sports injuries.
• Veterinary Pharmaceutical Products: Incorporated into topical treatments for pain and inflammation in animals.
• Pharmaceutical Intermediates: Serves as a crucial precursor in the synthesis of other diclofenac-based drug substances.
• Over-the-Counter (OTC) Topical Products: Used in consumer healthcare items for back pain, sprains, and strains.

Basic Information

Product Name	Diclofenac Diethylamine
CAS No.	78213-16-8
Molecular Formula	C20H25Cl2N2O2
Molecular Weight	396.33 g/mol
Synonyms	Diclofenac Diethylammonium; Diethylammonium Diclofenac; 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid compound with N-ethylethanamine (1:1); Diclofenac DEA; Voltaren® Diethylamine Salt; GP 45840; GP-45840; Diclofenac N,N-Diethylammonium
EINECS	Contact for details

Quality Control

Our Diclofenac Diethylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) that detail specifications including assay, related substances, residual solvents, and identification. Our quality commitment aligns with cGMP principles to ensure supply chain reliability and product consistency for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.