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1-Stearoyl-2-Caproyl-Sn-Glycero-3-Phosphocholine CAS NO 78119-50-3
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CAS No.:78119-50-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-Stearoyl-2-Caproyl-Sn-Glycero-3-Phosphocholine is a defined, high-purity phospholipid, a critical building block for advanced lipid-based formulations. This compound is essential for researchers and manufacturers requiring precise control over membrane biophysics and formulation stability. It is particularly valuable for the development of liposomes, lipid nanoparticles (LNPs), and other model membrane systems in the pharmaceutical, biotechnology, and advanced materials sectors.
Application
- Liposome & Lipid Nanoparticle (LNP) Formulation: A key synthetic phospholipid component for constructing stable, uniform vesicles for drug delivery, mRNA vaccines, and diagnostic agents.
- Biomimetic Membrane Research: Used to create defined model membranes for studying protein-lipid interactions, membrane permeability, and cellular processes.
- Pharmaceutical Excipient: Serves as a functional excipient in advanced parenteral and topical formulations to enhance solubility and bioavailability of active ingredients.
- Biophysical Studies: Essential for calorimetry (DSC), spectroscopy, and microscopy studies investigating phase behavior, packing, and fusion of lipid bilayers.
- Cosmetic & Dermal Delivery Systems: Incorporated into nanocarriers for the targeted and sustained release of active compounds in cosmetic and dermatological products.
- Reference Standard & Analytical Use: Employed as a high-purity standard for quantitative analysis (e.g., HPLC, LC-MS) of complex lipid mixtures in quality control and research laboratories.
Basic Information
| Product Name | 1-Stearoyl-2-Caproyl-Sn-Glycero-3-Phosphocholine |
| CAS No. | 78119-50-3 |
| Molecular Formula | C32H64NO8P |
| Molecular Weight | 621.83 g/mol |
| Synonyms | 18:0-6:0 PC; 1-Stearoyl-2-hexanoyl-sn-glycero-3-phosphocholine; SCPC; Phosphatidylcholine (18:0/6:0); 1-Octadecanoyl-2-hexanoyl-sn-glycero-3-phosphocholine; LysoPC(18:0/6:0); PC(18:0/6:0); (2R)-2-Hexanoyloxy-3-(octadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate |
| EINECS | Contact for details |
Quality Control
Our 1-Stearoyl-2-Caproyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for research and cGMP-guided formulation development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid or waxy solid |
| Identification (HPLC) | Conforms to reference standard |
| Identification (MS) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% (Area Percent) |
| Water Content (KF) | ≤ 1.0 % |
| Solvent Residue (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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