Description

1-(4-Butoxy-2-Butenyl)-4-Phenyl-4-Piperidinol Propionate Hydrochloride is a specialized pharmaceutical intermediate of significant interest in modern organic synthesis. This compound matters for its role as a key building block in the development of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. Pharmaceutical manufacturers and advanced research institutions require this high-purity intermediate to ensure the efficacy and consistency of their final drug products.

Application

• Pharmaceutical Intermediate: Primary use as a critical precursor in the synthesis of complex therapeutic agents.
• Neurological Research: Serves as a key scaffold in the development of compounds for CNS-related drug discovery programs.
• Process Chemistry: Used in scale-up and optimization of synthetic routes for API manufacturing under GMP conditions.
• Analytical Reference Standard: Employed as a high-purity standard for quality control and method validation in analytical laboratories.
• Academic & Contract Research: Utilized in universities and CROs for medicinal chemistry research and structure-activity relationship (SAR) studies.

Basic Information

Product Name	1-(4-Butoxy-2-Butenyl)-4-Phenyl-4-Piperidinol Propionate Hydrochloride
CAS No.	78033-80-4
Molecular Formula	C22H33NO4 • HCl
Molecular Weight	411.96 g/mol (Free base: 375.50 g/mol)
Synonyms	4-Phenyl-1-[4-(butoxy)-2-butenyl]-4-piperidinol propionate hydrochloride; 1-(4-Butoxy-2-butenyl)-4-phenyl-4-piperidinol propanoate hydrochloride; Propanoic acid, 1-(4-butoxy-2-butenyl)-4-phenyl-4-piperidinyl ester, hydrochloride; 4-Phenyl-1-(4-butoxybut-2-enyl)piperidin-4-yl propionate hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(4-Butoxy-2-Butenyl)-4-Phenyl-4-Piperidinol Propionate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.