Description

12,13-Epoxy-3α-[(Trimethylsilyl)Oxy]Trichothec-9-Ene-4β,8α,15-Triol 4,15-Diacetate 8-(4-Methylbutanoate) is a chemically modified trichothecene derivative, a class of compounds known for their potent biological activity. This high-purity intermediate is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for targeted synthesis and structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex bioactive molecules and potential drug candidates.
• Chemical Biology Research: Used as a molecular probe to study biological pathways and enzyme interactions related to trichothecene activity.
• Medicinal Chemistry: Serves as a core scaffold for the development and optimization of new chemical entities with targeted therapeutic effects.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in laboratories.
• Process Chemistry: Utilized in route scouting and scale-up studies for the production of specialized fine chemicals.
• Academic Research: Supports investigative studies in organic synthesis and natural product chemistry at universities and research institutes.

Basic Information

Product Name	12,13-Epoxy-3α-[(Trimethylsilyl)Oxy]Trichothec-9-Ene-4β,8α,15-Triol 4,15-Diacetate 8-(4-Methylbutanoate)
CAS No.	77882-85-0
Molecular Formula	C29H44O9Si
Molecular Weight	564.74 g/mol
Synonyms	4,15-Diacetyl-12,13-epoxytrichothec-9-en-3α-ol 8-isovalerate 3-trimethylsilyl ether; 3α-[(Trimethylsilyl)oxy]-12,13-epoxytrichothec-9-ene-4β,8α,15-triol 4,15-diacetate 8-(3-methylbutanoate); T-2 Toxin 3-acetate 8-isovalerate 3-TMS ether; 8-O-Isovalerylneosolaniol 3-TMS ether; Modified Trichothecene Derivative; T-2 Toxin Trimethylsilyl Ether Derivative; Contact for details on additional aliases.
EINECS	Contact for details

Quality Control

Our 12,13-Epoxy-3α-[(Trimethylsilyl)Oxy]Trichothec-9-Ene-4β,8α,15-Triol 4,15-Diacetate 8-(4-Methylbutanoate) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This compound is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.