Description

Peg6-(Ch2Co2H)2 CAS NO 77855-76-6 is a specialized, bifunctional polyethylene glycol derivative featuring terminal carboxylic acid groups. This molecular structure is critical for its role as a versatile linker and spacer in advanced chemical synthesis and bioconjugation. It is primarily sought after by research and development teams in the pharmaceutical, biotechnology, and advanced materials sectors. Its design enables precise modification and functionalization of surfaces, polymers, and biomolecules.

Application

• Bioconjugation and Drug Delivery: Serves as a hydrophilic, biocompatible linker for attaching drugs, peptides, or targeting ligands to carriers like antibodies or nanoparticles.
• Polymer Modification: Used as a macromonomer or cross-linking agent to introduce carboxylic acid functionality into polymer backbones for further reaction.
• Surface Functionalization: Enables the creation of carboxyl-terminated self-assembled monolayers (SAMs) on metal or oxide surfaces for sensor development and biomaterial coatings.
• Hydrogel Synthesis: Acts as a water-soluble cross-linker in the formation of hydrogels for biomedical applications such as tissue engineering scaffolds.
• Intermediate for Specialty Chemicals: Provides a platform for synthesizing more complex PEG derivatives, including those with activated esters (e.g., NHS, succinimidyl esters) for facile amide bond formation.
• Analytical Chemistry: Can be utilized in the modification of chromatography stationary phases to alter separation properties.

Basic Information

Product Name	Peg6-(Ch2Co2H)2
CAS No.	77855-76-6
Molecular Formula	C18H34O11
Molecular Weight	426.46 g/mol
Synonyms	15-Oxa-3,6,9,12-tetraoxapentacosanedioic acid; α,ω-Bis(carboxymethyl)hexaethylene glycol; Hexaethylene glycol diacetic acid; PEG-6 diacetic acid; 3,6,9,12,15-Pentaoxaheptacosanedioic acid; 2,2'-(Oxybis(ethane-2,1-diyloxy))bis(ethane-2,1-diyloxy))diacetic acid; HOOC-CH2-(OCH2CH2)6-O-CH2-COOH (common structural representation)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with high-purity standards for research and industrial use. Each lot is characterized using advanced analytical techniques to confirm identity, purity, and functional group integrity. Certificates of Analysis (COA) detailing specific test results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Acid Value (Titration)	Theoretical range
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.