Description

2-Chloro-6-(3-Trifluoromethylphenoxy) Pyrazine is a high-value, halogenated pyrazine derivative with a trifluoromethylphenoxy substituent, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, combining electron-withdrawing groups, makes it an essential building block for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazine core.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Chloro-6-(3-Trifluoromethylphenoxy) Pyrazine
CAS No.	77782-74-2
Molecular Formula	C11H6ClF3N2O
Molecular Weight	274.63 g/mol
Synonyms	2-Chloro-6-[(3-(trifluoromethyl)phenyl]oxy]pyrazine; 2-Chloro-6-(α,α,α-trifluoro-m-tolyloxy)pyrazine; 6-Chloro-3-(3-trifluoromethylphenoxy)pyrazine; Pyrazine, 2-chloro-6-[(3-(trifluoromethyl)phenyl]oxy]-; 2-Chloro-6-(3-trifluoromethylphenoxy)pyrazine; 77782-74-2; m-Trifluoromethylphenyl 6-chloropyrazin-2-yl ether
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-(3-Trifluoromethylphenoxy) Pyrazine is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via techniques such as HPLC, GC, NMR, and MS is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.