Description

(5Beta,7Alpha,12Alpha)-7,12-Dihydroxychol-3-En-24-Oic Acid Methyl Ester is a key synthetic intermediate in the production of bile acids and their derivatives. This compound is valued for its defined stereochemistry and high purity, which are critical for ensuring the consistency and efficacy of downstream pharmaceutical products. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for the development of therapeutic agents and biochemical research.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of ursodeoxycholic acid (UDCA) and other therapeutic bile acids.
• Biochemical Research: Used as a reference standard and precursor in metabolic pathway studies and enzyme inhibition assays.
• Steroid Chemistry: Serves as a versatile starting material for the preparation of various steroidal compounds with modified side chains.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.

Basic Information

Product Name	(5Beta,7Alpha,12Alpha)-7,12-Dihydroxychol-3-En-24-Oic Acid Methyl Ester
CAS No.	77731-11-4
Molecular Formula	C25H40O5
Molecular Weight	420.59 g/mol
Synonyms	Methyl 3β-Hydroxy-7α,12α-dihydroxy-5β-chol-24-enoate; Methyl 7α,12α-Dihydroxy-5β-chol-3-en-24-oate; 7α,12α-Dihydroxy-5β-chol-3-en-24-oic Acid Methyl Ester; 5β-Chol-3-ene-7α,12α-diol-24-oic Acid Methyl Ester; CAS 77731-11-4
EINECS	Contact for details

Quality Control

Our (5Beta,7Alpha,12Alpha)-7,12-Dihydroxychol-3-En-24-Oic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediates. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.