Description

(5Z,8Z,11Z)-14,15-Dihydroxyicosa-5,8,11-Trienoic Acid is a specialized dihydroxy fatty acid derivative, serving as a key intermediate and reference standard in advanced biochemical research. This compound is valued for its role in studying eicosanoid pathways, lipid signaling, and inflammation-related biological mechanisms. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of high-purity biochemical reagents.

Application

• Biochemical Research Standard: Used as a high-purity reference compound for analytical method development and validation in lipidomics.
• Pharmaceutical Intermediate: Serves as a critical synthetic precursor in the development of novel anti-inflammatory and pro-resolving lipid mediators.
• Cell Signaling Studies: Employed in vitro and in vivo to investigate the biological activity and metabolism of dihydroxy-eicosatrienoic acids (DHETs).
• Enzyme Substrate/Inhibitor Research: Applied in assays to study the function of cytochrome P450 epoxygenases, soluble epoxide hydrolase (sEH), and related enzymes.
• Metabolite Identification: Acts as a definitive standard in LC-MS and GC-MS workflows for identifying and quantifying arachidonic acid metabolites.
• Production of Specialized Reagents: Used in the synthesis of labeled analogs (e.g., deuterated, 13C) for use as internal standards in mass spectrometry.

Basic Information

Product Name	(5Z,8Z,11Z)-14,15-Dihydroxyicosa-5,8,11-Trienoic Acid
CAS No.	77667-09-5
Molecular Formula	C₂₀H₃₄O₄
Molecular Weight	338.48 g/mol
Synonyms	14,15-Dihydroxy-5Z,8Z,11Z-eicosatrienoic Acid; 14,15-DHET; 14,15-Dihydroxy-5,8,11-eicosatrienoic Acid; (5Z,8Z,11Z)-14,15-Dihydroxyeicosa-5,8,11-trienoic Acid; 14,15-Dihydroxyicosatrienoic Acid; 14(15)-Epoxy-5,8,11-eicosatrienoic Acid Diol; 14,15-Epoxy-5,8,11-eicosatrienoic Acid Diol; Arachidonic Acid 14,15-Diol
EINECS	Contact for details

Quality Control

Our (5Z,8Z,11Z)-14,15-Dihydroxyicosa-5,8,11-Trienoic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area Percent)
Assay (by HPLC)	≥ 90% (by weight)
Solubility	Soluble in ethanol, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.