Description

(-)-Cladospolide A is a chiral macrolide natural product isolated from various fungal species. This compound is of significant interest in organic synthesis and medicinal chemistry due to its unique structural framework and associated biological activities. It serves as a valuable building block and reference standard for researchers in pharmaceutical development, agrochemical research, and advanced material science.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the synthesis of novel bioactive molecules and drug candidates.
• Medicinal Chemistry Studies: For structure-activity relationship (SAR) studies and as a lead compound for investigating new therapeutic pathways.
• Biochemical Research: Used as a tool compound to study biological mechanisms and enzyme interactions in academic and industrial laboratories.
• Organic Synthesis: Serves as a sophisticated chiral starting material or template for the total synthesis of complex natural products and macrolides.
• Agrochemical Research: Investigated for potential applications in developing new crop protection agents with novel modes of action.
• Analytical Standard: Employed as a high-purity certified reference material (CRM) for analytical method development and quality control in related manufacturing.

Basic Information

Product Name	(-)-Cladospolide A
CAS No.	77663-54-8
Molecular Formula	C16H26O5
Molecular Weight	298.37 g/mol
Synonyms	(3R,5R,8S,9S,10R,13S,15S)-3-Hydroxy-5,8,10,14-tetramethyl-4,17-dioxabicyclo[13.3.1]heptadec-14-ene-7,16-dione; Cladospolide A; (-)-Cladospolide A; (3R,5R,8S,9S,10R,13S,15S)-Cladospolide A; Cladospolide A, (-)-; L-755,805 (related macrolide research compound).
EINECS	Contact for details

Quality Control

Our (-)-Cladospolide A is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and MS for identity verification. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. Allow the container to reach room temperature in a dry environment before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.