Description

Siderochelin A is a naturally occurring siderophore — a low-molecular-weight, iron-chelating compound produced by microorganisms under iron-limited conditions. It plays a critical role in microbial iron acquisition and has gained increasing interest for its potential in biomedical research, including antimicrobial adjuvant development and targeted metal delivery systems. Researchers in pharmaceutical discovery, microbiology, and bioinorganic chemistry rely on high-purity Siderochelin A CAS NO 77550-87-9 for mechanistic studies and structure–activity relationship investigations.

Application

• Iron metabolism and transport studies in bacterial and fungal pathogens
• Development of siderophore-antibiotic conjugates (‘Trojan horse’ antibiotics)
• Chelation therapy research for iron-overload disorders
• Biological probe for imaging iron homeostasis in cell culture models
• Reference standard in HPLC and LC-MS method validation for siderophore analysis
• Tool compound for investigating host–pathogen interactions involving iron sequestration
• Enzyme inhibition assays targeting siderophore biosynthesis pathways (e.g., nonribosomal peptide synthetases)
• Material for functionalized nanocarrier design in targeted metal ion delivery

Basic Information

Product Name	Siderochelin A
CAS No.	77550-87-9
Molecular Formula	C36H51N7O12
Molecular Weight	797.85 g/mol
Synonyms	Siderochelin A; Siderochelin-A; N-(2,3-Dihydroxybenzoyl)-L-lysyl-L-serine-L-threonine-L-ornithine cyclic ester; Rhizoferrin analog A; Fungal siderophore A; Iron-chelating peptide A; CAS 77550-87-9; Microbial iron scavenger A
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. Each batch of Siderochelin A is verified for identity (HPLC retention time, IR spectral match), assay purity (≥98.0% by HPLC), residual solvent content (per ICH Q3C), and absence of microbial contamination. Testing adheres to principles aligned with ACS Reagent Grade and ISO 9001-certified laboratory practices.

Storage

Preserve in a tightly closed container, protected from light. Store at 2–8 °C under inert atmosphere (argon or nitrogen) to prevent oxidation and moisture uptake. Due to its hygroscopic nature, minimize exposure to ambient humidity during handling. Keep away from strong acids, strong alkalis, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Single impurity ≤0.5%; Total impurities ≤2.0%
Residual Solvents (GC)	Meets ICH Q3C limits
Water Content (Karl Fischer)	≤5.0%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.