Description

Northienamycin CAS NO 77550-86-8 is a potent β-lactam antibiotic belonging to the carbapenem class, known for its broad-spectrum activity against a wide range of Gram-positive and Gram-negative bacteria. This compound is of significant interest in pharmaceutical research and development for creating novel antibacterial agents to combat resistant strains. It serves as a critical intermediate and reference standard for researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced carbapenem antibiotics.
• Antibacterial Research: Used as a reference standard in microbiological assays and studies of β-lactamase inhibition.
• Drug Discovery & Development: A vital compound for screening and developing new antimicrobial therapies against multidrug-resistant pathogens.
• Biochemical Studies: Employed in research to understand the mechanism of action and structure-activity relationships (SAR) of carbapenems.
• Quality Control: Utilized as an analytical reference standard for the identification and assay of related pharmaceutical products.

Basic Information

Item	Details
Product Name	Northienamycin
CAS No.	77550-86-8
Molecular Formula	C12H16N2O6S
Molecular Weight	316.33 g/mol
Synonyms	Northienamycin; (5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-[[(3S,5S)-5-[(sulfomethylamino)carbonyl]-3-pyrrolidinyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; Carbapenem antibiotic derivative; Antibiotic NK-1001; NK-1001
EINECS	Contact for details

Quality Control

Our Northienamycin is produced and tested under strict quality management systems. Each batch undergoes comprehensive analysis to ensure identity, purity, and potency, meeting the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing specific test results, including assay by HPLC and related substance profiles, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.