Description

Ethyl (41S,12R,13As)-13A-Ethyl-12-Hydroxy-2,3,41,5,6,12,13,13A-Octahydro-1H-Indolo[3,2,1-De]Pyrido[3,2,1-Ij][1,5]Naphthyridine-12-Carboxylate is a complex, high-purity organic compound with a defined stereochemistry, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in enabling the efficient and stereoselective construction of intricate molecular architectures, which is essential for developing novel active pharmaceutical ingredients (APIs) and other high-value fine chemicals. This product is primarily needed by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in process development and the synthesis of complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key chiral building block for the research and development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for complex alkaloid-like molecules and other nitrogen-containing heterocycles.
• Academic & Contract Research: Serves as a valuable reference standard and starting material for methodological studies in organic synthesis and catalysis.
• Fine Chemical Synthesis: Employed in the production of specialized ligands, catalysts, or other high-value chemical entities requiring precise stereochemical control.

Basic Information

Product Name	Ethyl (41S,12R,13As)-13A-Ethyl-12-Hydroxy-2,3,41,5,6,12,13,13A-Octahydro-1H-Indolo[3,2,1-De]Pyrido[3,2,1-Ij][1,5]Naphthyridine-12-Carboxylate
CAS No.	77549-92-9
Molecular Formula	C23H30N2O3
Molecular Weight	382.50 g/mol
Synonyms	Ethyl 13a-ethyl-12-hydroxy-2,3,4a,5,6,12,13,13a-octahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate; (12R,13aS)-13a-Ethyl-12-hydroxy-1,2,3,4,4a,5,6,12,13,13a-decahydroindolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylic acid ethyl ester; Yohimbane derivative intermediate; Complex polycyclic alkaloid intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.