Description

3A,4,4A,5,6,7,9,9A-Octahydro-4,5-Dihydroxy-4A,8-Dimethyl-3-Methyleneazuleno[6,5-B]Furan-2(3H)-One is a complex sesquiterpene lactone derivative with a fused azulene-furan structure, offering a unique chemical scaffold for advanced synthesis. This compound is valued for its intricate molecular architecture, which makes it a versatile intermediate in the development of novel bioactive molecules. It is primarily sought by research and development teams in the pharmaceutical and fine chemical sectors for use in medicinal chemistry and as a building block for specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential drug candidates, particularly those targeting anti-inflammatory or anticancer pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Fine Chemical Synthesis: Acts as a precursor for the preparation of complex natural product analogs and specialty fragrances.
• Academic & Industrial R&D: Employed in chemical research to explore novel organic reactions and catalytic transformations of sesquiterpenoid systems.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and compound identification.

Basic Information

Product Name	3A,4,4A,5,6,7,9,9A-Octahydro-4,5-Dihydroxy-4A,8-Dimethyl-3-Methyleneazuleno[6,5-B]Furan-2(3H)-One
CAS No.	77353-83-4
Molecular Formula	C₁₅H₂₀O₄
Molecular Weight	264.32 g/mol
Synonyms	4,5-Dihydroxy-4a,8-dimethyl-3-methylidene-3a,4,4a,5,6,7,9,9a-octahydroazuleno[6,5-b]furan-2-one; (3aS,4R,4aR,5R,9aR)-4,5-Dihydroxy-4a,8-dimethyl-3-methylidene-3a,4,4a,5,6,7,9,9a-octahydroazuleno[6,5-b]furan-2-one; Azuleno[6,5-b]furan-2(3H)-one derivative; Sesquiterpene lactone intermediate; Dihydroxy-dimethyl-methyleneazulenofuranone
EINECS	Contact for details

Quality Control

Our production of 3A,4,4A,5,6,7,9,9A-Octahydro-4,5-Dihydroxy-4A,8-Dimethyl-3-Methyleneazuleno[6,5-B]Furan-2(3H)-One adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. All materials are characterized using advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.