Description

Flatugel CAS NO 77321-50-7 is a high-purity pharmaceutical excipient, specifically a cross-linked polyvinylpyrrolidone (crospovidone). This compound is valued for its exceptional disintegrant properties, which are critical for ensuring the rapid and complete breakdown of solid dosage forms in the body. It is an essential material for formulators in the pharmaceutical industry seeking to enhance drug bioavailability and dissolution rates. Its consistent performance makes it a reliable choice for the production of tablets and capsules.

Application

• Pharmaceutical Tablet Disintegrant: Primary use in oral solid dosage forms to promote rapid tablet disintegration and drug release.
• Capsule Formulation: Used in hard gelatin and vegetarian capsules to improve dissolution and content uniformity.
• Suspension Stabilizer: Acts as a suspending agent in liquid and semi-solid pharmaceutical preparations.
• Binder in Wet Granulation: Functions as a binder in granulation processes while maintaining excellent disintegration properties.
• Food Supplement Tablets: Employed in the manufacture of nutraceutical and dietary supplement tablets for quick disintegration.
• Taste-Masking Agent: Used in formulations to mask unpleasant tastes of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Flatugel CAS NO 77321-50-7
CAS No.	77321-50-7
Molecular Formula	(C6H9NO)n
Molecular Weight	~1,000,000 (Typical average)
Synonyms	Crospovidone; Cross-linked PVP; Polyvinylpolypyrrolidone; PVPP; Insoluble polyvinylpyrrolidone; E1202; 1-Ethenyl-2-pyrrolidinone homopolymer, cross-linked; Kollidon CL
EINECS	Contact for details

Quality Control

Our Flatugel is manufactured under strict quality management systems. Each batch is tested to ensure it meets stringent specifications for pharmaceutical applications, including purity, particle size distribution, and swelling capacity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant parameters. The product can be supplied in grades compliant with major pharmacopoeial standards such as USP-NF, Ph. Eur., and JP.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect the product from atmospheric moisture.

Specification

Item	Specification
Appearance	White or almost white, free-flowing powder
Identification (IR)	Conforms
Assay (on dried basis)	NLT 11.0% and NMT 12.8% Nitrogen
Water (KF)	NMT 6.0%
Residue on Ignition	NMT 0.1%
Heavy Metals	NMT 10 ppm
Particle Size Distribution	As per customer grade requirement
Swelling Volume	Contact for details
Microbial Limits	Meets Ph. Eur. 2.6.12 / USP <61> requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.