Description

Teduglutide [Usan] is a synthetic analog of human glucagon-like peptide-2 (GLP-2) designed to enhance intestinal absorption and mucosal repair. This peptide is critical for therapeutic applications targeting intestinal failure and related malabsorption syndromes. It is primarily required by pharmaceutical manufacturers and research institutions developing advanced treatments for gastrointestinal disorders and short bowel syndrome.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the active component in injectable formulations for the treatment of Short Bowel Syndrome (SBS).
• Clinical Research & Development: Serves as a key reference standard and investigational material in preclinical and clinical studies for gastrointestinal therapies.
• Biopharmaceutical Manufacturing: Used in the production of finished dosage forms under current Good Manufacturing Practice (cGMP) guidelines.
• Metabolic Disorder Research: Applied in laboratory studies to investigate mechanisms of intestinal adaptation, nutrient absorption, and mucosal growth.
• Drug Delivery System Development: Utilized in research for developing sustained-release or novel delivery platforms for peptide therapeutics.

Basic Information

Product Name	Teduglutide [Usan]
CAS No.	287714-30-1
Molecular Formula	C164H252N44O55S
Molecular Weight	3752.1 g/mol
Synonyms	Recombinant human GLP-2 (1-33), h[Gly2]GLP-2; GLP-2 (human, rat); Gattex; Revestive; Teduglutide recombinant; ALX-0600; GLP-2 analog; Glucagon-like peptide 2 (1-33) (human) (Gly2 analog)
EINECS	Contact for details

Quality Control

Our Teduglutide is manufactured and controlled to meet stringent pharmaceutical-grade specifications. Quality assurance includes comprehensive testing for identity, purity, potency, and related substances. A Certificate of Analysis (COA) is provided with each batch, detailing results from advanced analytical techniques such as HPLC, MS, and peptide mapping to ensure compliance with relevant pharmacopeial standards and customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled under appropriate conditions to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (Related Substances)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Bacterial Endotoxins	< 10 EU/mg
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.