Description

Hydroxy-Peg4-Ch2Co2Me is a high-purity, functionalized polyethylene glycol (PEG) derivative, specifically a methyl ester-terminated tetraethylene glycol compound. This versatile chemical building block is critical for introducing hydrophilic spacing and biocompatible linkers in advanced synthesis. It is essential for researchers and manufacturers in the pharmaceutical and bioconjugation sectors who require reliable, well-characterized intermediates for developing novel therapeutics, diagnostics, and advanced materials.

Application

• Pharmaceutical Linker: A key intermediate in the synthesis of Antibody-Drug Conjugates (ADCs) and other targeted drug delivery systems.
• Bioconjugation Reagent: Used to modify proteins, peptides, and other biomolecules to enhance solubility, stability, and pharmacokinetic properties.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent in the development of hydrogels and smart polymeric materials.
• Proteomics Research: Employed in the preparation of affinity tags and tools for mass spectrometry analysis.
• Diagnostic Reagent Synthesis: Used in creating components for immunoassays and biosensors.
• Surface Modification: Facilitates the PEGylation of nanoparticles and surfaces to reduce immunogenicity and improve biocompatibility.

Basic Information

Product Name	Hydroxy-Peg4-Ch2Co2Me
CAS No.	77303-64-1
Molecular Formula	C13H26O8
Molecular Weight	310.34 g/mol
Synonyms	2-[2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]ethoxy]acetic acid methyl ester; Methyl 2,5,8,11-tetraoxatridecan-13-oate; Tetraethylene glycol monomethyl ether acetate methyl ester; HO-PEG4-CH2COOMe; 15-Hydroxy-4,7,10,13-tetraoxapentadecan-1-oic acid methyl ester; PEG4 methyl ester; Methyl-PEG4-OH
EINECS	Contact for details

Quality Control

Our Hydroxy-Peg4-Ch2Co2Me is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports applications in GMP and research environments where material traceability and reliability are paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.