share

1-(tert-Butoxycarbonyl)-4-((2-Pyridyl)Methyl)Piperazine CAS NO 77278-93-4


Unit Price:

CAS No.:77278-93-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(tert-Butoxycarbonyl)-4-((2-Pyridyl)Methyl)Piperazine is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core protected by a Boc (tert-butoxycarbonyl) group and functionalized with a 2-pyridylmethyl substituent. This compound matters as a critical building block for medicinal chemists, enabling the synthesis of complex molecules with potential biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new drug candidates, particularly in areas requiring sophisticated nitrogen-containing heterocycles.

Application

  • Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
  • Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
  • Ligand Synthesis: Employed in the preparation of complex ligands for catalysis or metal coordination chemistry due to its nitrogen donor atoms.
  • Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and enzyme functions.
  • Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name 1-(tert-Butoxycarbonyl)-4-((2-Pyridyl)Methyl)Piperazine
CAS No. 77278-93-4
Molecular Formula C15H23N3O2
Molecular Weight 277.36 g/mol
Synonyms 1-Boc-4-(2-Pyridylmethyl)piperazine; 1-N-Boc-4-(2-Pyridinylmethyl)piperazine; 4-(Pyridin-2-ylmethyl)piperazine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(pyridin-2-ylmethyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(2-pyridinylmethyl)piperazine; Boc-4-(2-Picolyl)piperazine; N-Boc-4-(2-Pyridylmethyl)piperazine
EINECS Contact for details

Quality Control

Our 1-(tert-Butoxycarbonyl)-4-((2-Pyridyl)Methyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Assay (HPLC) ≥98.0%
Water Content (KF) ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

Complete Your RFQ

0/ 2000

why choose us

Trusted Manufacturer

With our own production facilities, we ensure consistent quality, reliable supply, and full traceability.

Rigorous Quality Assurance

Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.

Advanced R&D Expertise

Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.