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1-(tert-Butoxycarbonyl)-4-((2-Pyridyl)Methyl)Piperazine CAS NO 77278-93-4
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CAS No.:77278-93-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-(tert-Butoxycarbonyl)-4-((2-Pyridyl)Methyl)Piperazine is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core protected by a Boc (tert-butoxycarbonyl) group and functionalized with a 2-pyridylmethyl substituent. This compound matters as a critical building block for medicinal chemists, enabling the synthesis of complex molecules with potential biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new drug candidates, particularly in areas requiring sophisticated nitrogen-containing heterocycles.
Application
- Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
- Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
- Ligand Synthesis: Employed in the preparation of complex ligands for catalysis or metal coordination chemistry due to its nitrogen donor atoms.
- Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and enzyme functions.
- Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
Basic Information
| Product Name | 1-(tert-Butoxycarbonyl)-4-((2-Pyridyl)Methyl)Piperazine |
| CAS No. | 77278-93-4 |
| Molecular Formula | C15H23N3O2 |
| Molecular Weight | 277.36 g/mol |
| Synonyms | 1-Boc-4-(2-Pyridylmethyl)piperazine; 1-N-Boc-4-(2-Pyridinylmethyl)piperazine; 4-(Pyridin-2-ylmethyl)piperazine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(pyridin-2-ylmethyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(2-pyridinylmethyl)piperazine; Boc-4-(2-Picolyl)piperazine; N-Boc-4-(2-Pyridylmethyl)piperazine |
| EINECS | Contact for details |
Quality Control
Our 1-(tert-Butoxycarbonyl)-4-((2-Pyridyl)Methyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Conforms to reference |
| Assay (HPLC) | ≥98.0% |
| Water Content (KF) | ≤0.5% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | ≤20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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