Description

4-[(4-Fluorophenyl)Methyl]-1,1-Piperazinecarboxylic Acid, 1,1-Dimethylethyl Ester is a high-purity, protected piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate, enabling the development of novel active pharmaceutical ingredients (APIs) with enhanced pharmacological profiles. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its fluorinated aromatic and piperazine motifs.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis projects requiring a protected, functionalized piperazine scaffold.
• Material Science Research: Potential monomer or precursor for specialty polymers and advanced functional materials.

Basic Information

Item	Detail
Product Name	4-[(4-Fluorophenyl)Methyl]-1,1-Piperazinecarboxylic Acid, 1,1-Dimethylethyl Ester
CAS No.	77278-77-4
Molecular Formula	C17H25FN2O2
Molecular Weight	308.40 g/mol
Synonyms	tert-Butyl 4-[(4-fluorophenyl)methyl]piperazine-1-carboxylate; 1-Boc-4-(4-fluorobenzyl)piperazine; N-Boc-4-(4-fluorobenzyl)piperazine; 4-(4-Fluorobenzyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(4-fluorobenzyl)piperazine; tert-Butyl 4-(4-fluorobenzyl)-1-piperazinecarboxylate; 77278-77-4; 4-(4-Fluorobenzyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our production of 4-[(4-Fluorophenyl)Methyl]-1,1-Piperazinecarboxylic Acid, 1,1-Dimethylethyl Ester adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. We provide detailed Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.