Description

(4-Boc-Piperazin-1-Yl)-Acetamide is a high-purity, protected piperazine derivative widely utilized as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Peptidomimetic Chemistry: Serves as a versatile scaffold for constructing peptide-like molecules with enhanced metabolic stability.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal catalysis and molecular recognition applications.
• Agrochemical Synthesis: Employed as a building block in the research and development of new crop protection agents.
• Custom Chemical Synthesis: Provides a protected amine handle for multi-step synthetic routes requiring selective deprotection strategies.

Basic Information

Product Name	(4-Boc-Piperazin-1-Yl)-Acetamide
CAS No.	77278-70-7
Molecular Formula	C11H21N3O3
Molecular Weight	243.30 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-4-(carbamoylmethyl)piperazine; N-[(tert-Butoxycarbonyl)piperazin-1-yl]acetamide; 1-Acetamido-4-Boc-piperazine; tert-Butyl 4-(2-amino-2-oxoethyl)piperazine-1-carboxylate; 2-(4-[(tert-Butoxy)carbonyl]piperazin-1-yl)acetamide; Boc-Pip-Acetamide; (4-Boc-Piperazin-1-yl)acetamide
EINECS	Contact for details

Quality Control

Our (4-Boc-Piperazin-1-Yl)-Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.