Description

1-Boc-4-(2-Pyridinyl)-Piperazine is a high-purity, protected piperazine derivative widely used as a critical building block in organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in pharmaceutical research. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to introduce the 4-(2-pyridinyl)piperazine pharmacophore into new chemical entities.
• Ligand Synthesis: Serves as a building block for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Agrochemical Development: Employed in the research and synthesis of novel crop protection agents and pesticides.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes under cGMP conditions.
• Chemical Biology Probes: Useful for constructing molecular probes to study biological pathways and protein interactions.

Basic Information

Product Name	1-Boc-4-(2-Pyridinyl)-Piperazine
CAS No.	77278-62-7
Molecular Formula	C14H21N3O2
Molecular Weight	263.34 g/mol
Synonyms	tert-Butyl 4-(pyridin-2-yl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(2-pyridyl)piperazine; 4-(2-Pyridinyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; N-Boc-4-(2-pyridinyl)piperazine; 1-Boc-4-(2-pyridyl)piperazine; 77278-62-7; 4-(Pyridin-2-yl)piperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(2-Pyridinyl)-Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.