Description

tert-Butyl 4-(3-Methoxybenzyl)Piperazine-1-Carboxylate is a high-purity, protected piperazine derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the efficient construction of complex molecules with precise structural control. Pharmaceutical researchers and fine chemical manufacturers need it for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those containing a piperazine pharmacophore.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for the discovery of new therapeutic agents.
• CNS-Active Compound Synthesis: Building block for potential antipsychotics, antidepressants, and other neuroactive molecules.
• Custom Synthesis & Contract Manufacturing: Essential starting material for the production of bespoke compounds and advanced intermediates on a commercial scale.
• Chemical Biology & Proteomics: Can be utilized in the development of chemical probes and tools for studying biological systems.
• Agrochemical Research: Intermediate in the development of new crop protection agents and pesticides.

Basic Information

Item	Detail
Product Name	tert-Butyl 4-(3-Methoxybenzyl)Piperazine-1-Carboxylate
CAS No.	77278-57-0
Molecular Formula	C17H26N2O3
Molecular Weight	306.40 g/mol
Synonyms	1-Boc-4-(3-Methoxybenzyl)piperazine; tert-Butyl 4-[(3-Methoxyphenyl)methyl]piperazine-1-carboxylate; 4-(3-Methoxybenzyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(3-methoxybenzyl)piperazine; N-Boc-4-(3-Methoxybenzyl)piperazine; Boc-4-(3-Methoxybenzyl)piperazine; 77278-57-0; 1,4-Piperazinedicarboxylic acid, 4-[(3-methoxyphenyl)methyl]-, 1-(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Methoxybenzyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all specifications and test results. We are committed to meeting the stringent requirements of GMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.