Description

1-Piperazinecarboxylic Acid, 4-Benzoyl-, 1,1-Dimethylethyl Ester is a high-purity, protected piperazine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the piperazine moiety contributes to biological activity.
• Peptidomimetic Chemistry: Serves as a protected scaffold for constructing peptide analogs and mimetics in medicinal chemistry programs.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organocatalysts for asymmetric synthesis.
• Custom Chemical Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Academic Research: A valuable reagent for methodological studies and the exploration of new synthetic pathways in university and institutional labs.

Basic Information

Product Name	1-Piperazinecarboxylic Acid, 4-Benzoyl-, 1,1-Dimethylethyl Ester
CAS No.	77278-38-7
Molecular Formula	C16H22N2O3
Molecular Weight	290.36 g/mol
Synonyms	4-Benzoyl-1-Boc-piperazine; tert-Butyl 4-benzoylpiperazine-1-carboxylate; 1-Boc-4-benzoylpiperazine; N-Boc-4-benzoylpiperazine; 1-(tert-Butoxycarbonyl)-4-benzoylpiperazine; 4-Benzoylpiperazine-1-carboxylic acid tert-butyl ester; Boc-4-benzoylpiperazine; Piperazine-1-carboxylic acid, 4-benzoyl-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarboxylic Acid, 4-Benzoyl-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with client specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.