Description

Leukotriene C3 CAS NO 77209-77-9 is a potent cysteinyl leukotriene (CysLT) and a key mediator in inflammatory and allergic responses. This compound is essential for advanced biochemical research and pharmaceutical development targeting respiratory and inflammatory diseases. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focused on immunology and respiratory pharmacology.

Application

• Biochemical Research: Used as a high-purity reference standard in studies of leukotriene biosynthesis, metabolism, and receptor interactions.
• Pharmaceutical Development: Serves as a critical intermediate or analytical standard in the development of drugs targeting asthma, allergic rhinitis, and other inflammatory conditions.
• Diagnostic Assays: Employed in the calibration and validation of immunoassays (e.g., ELISA) designed to quantify leukotriene levels in biological samples.
• Cell Signaling Studies: Applied in vitro to investigate the role of cysteinyl leukotrienes in cellular signaling pathways related to inflammation and smooth muscle contraction.
• Academic Research: A vital tool for universities and research institutes exploring the pathophysiology of anaphylaxis and other hypersensitivity reactions.
• Quality Control: Acts as a system suitability standard in the HPLC or LC-MS/MS analysis of related pharmaceutical compounds and biological matrices.

Basic Information

Product Name	Leukotriene C3
CAS No.	77209-77-9
Molecular Formula	C₂₈H₄₃N₃O₈S
Molecular Weight	581.73 g/mol
Synonyms	LTC3; (5S,6R)-6-[(1R,2E,4E,6Z,9Z)-1-[(2S)-2-Amino-2-carboxyethyl]sulfanyl-2,4,6,9-heptadecatetraen-1-yl]-5-hydroxy-7,9,11,14-icosatetraenoic acid; 5(S)-Hydroxy-6(R)-S-glutathionyl-7,9-trans-11,14-cis-eicosatetraenoic Acid; S-(1-[(4Z,7Z,10Z,13Z)-1-Carboxy-16-[(1S,2R)-1-hydroxy-2-[(5S)-5-hydroxy-6-oxido-6-oxohexyl]cyclopropyl]hexadeca-4,7,10,13-tetraen-1-yl]vinyl)-L-cysteinylglycine
EINECS	Contact for details

Quality Control

Our Leukotriene C3 is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by HPLC and mass spectrometry. We adhere to relevant standards for high-purity biochemicals to support GLP and GMP environments.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. This product is easily oxidized and moisture-sensitive; allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and exposure.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content	≤ 1.0% (KF)
Solvent Residues	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.