Description

Delta(1)-Thienamycin is a potent, broad-spectrum carbapenem antibiotic and a key intermediate in the synthesis of more complex β-lactam antibiotics. This compound is of critical importance in pharmaceutical research and development for creating next-generation antibacterial agents to combat resistant pathogens. It is primarily utilized by pharmaceutical manufacturers, research institutions, and fine chemical suppliers focused on advanced antibiotic synthesis and development.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of the carbapenem antibiotic, Imipenem, and other related β-lactam drugs.
• Antibacterial Research: Used as a reference standard and active scaffold in microbiological and pharmacological studies to investigate new mechanisms of action against Gram-positive and Gram-negative bacteria.
• Fine Chemical Synthesis: Employed in the development and scale-up of novel antibiotic compounds within R&D laboratories and pilot plants.
• Biochemical Studies: Utilized in enzymatic studies to understand bacterial cell wall synthesis and the inhibition of penicillin-binding proteins (PBPs).

Basic Information

Product Name	Delta(1)-Thienamycin
CAS No.	77171-32-5
Molecular Formula	C11H16N2O4S
Molecular Weight	272.32 g/mol
Synonyms	(5R,6S)-3-[(2S)-2-Amino-2-carboxyethyl]sulfanyl-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; (5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-[(2S)-2-amino-2-carboxyethyl]thio-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; Thienamycin; N-Acetyl Thienamycin; Antibiotic MK 0787; Antibiotic MK-0787
EINECS	Contact for details

Quality Control

Our Delta(1)-Thienamycin is manufactured under strict quality management systems to ensure high purity and consistency suitable for pharmaceutical research and synthesis. Each batch is tested using advanced analytical techniques, including HPLC and NMR, to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.