Description

(+/-)-15-Hydroxy-11Z,13E-Eicosadienoic Acid CAS NO 77159-57-0 is a bioactive eicosanoid derivative, specifically a hydroxylated eicosadienoic acid, that serves as a key intermediate in the study of lipid signaling pathways. This compound is of significant interest for its role as a precursor in the biosynthesis of various oxylipins and prostanoids, which are crucial mediators in physiological and inflammatory processes. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors for drug discovery, biochemical research, and the development of analytical standards.

Application

• Biochemical Research: Used as a critical standard and intermediate in the study of lipoxygenase and cyclooxygenase pathways, inflammation, and cell signaling.
• Pharmaceutical Development: Serves as a key building block or reference compound in the synthesis and development of novel anti-inflammatory agents and lipid-based therapeutics.
• Analytical Reference Standard: Employed in HPLC, GC-MS, and other analytical methods for the quantification and identification of related eicosanoids in biological samples.
• Nutraceutical & Cosmetic Research: Investigated for potential applications in skincare formulations and dietary supplements targeting inflammatory responses.
• Academic Research: Essential for universities and research institutes conducting fundamental studies on lipid metabolism and eicosanoid biology.
• Chemical Synthesis: Acts as a versatile chiral synthon for the preparation of more complex, stereochemically defined lipid molecules.

Basic Information

Product Name	(+/-)-15-Hydroxy-11Z,13E-Eicosadienoic Acid
CAS No.	77159-57-0
Molecular Formula	C20H36O3
Molecular Weight	324.50 g/mol
Synonyms	15-HETE; 15-Hydroxyeicosatetraenoic Acid (racemic mixture); 15(S)-HETE (racemic); 15-Hydroxy-11-cis,13-trans-eicosadienoic Acid; (±)-15-HETE; 15-Hydroxy-5,8,11,13-eicosatetraenoic Acid; 15-Lipoxygenase metabolite; 15-Hydroxyarachidonic Acid
EINECS	Contact for details

Quality Control

Our (+/-)-15-Hydroxy-11Z,13E-Eicosadienoic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. This product is hygroscopic and light-sensitive; allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 90% (by GC or HPLC)
Water Content (KF)	≤ 1.0%
Solubility	Soluble in ethanol, DMSO, and common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.