Description

Verrucarin L CAS NO 77101-87-2 is a macrocyclic trichothecene mycotoxin, a secondary metabolite produced by certain fungi. This compound is of significant interest in biochemical and pharmacological research due to its potent biological activity, particularly as a protein synthesis inhibitor. It serves as a critical reference standard and research tool for scientists in toxicology, mycology, and drug discovery. Researchers and quality control laboratories in the pharmaceutical, agricultural, and food safety sectors require this high-purity compound for analytical method development and toxicological studies.

Application

• Pharmaceutical Research: Used as a reference standard in the study of trichothecene toxicity mechanisms and the development of potential inhibitors or detoxification strategies.
• Toxicology & Food Safety: Employed in the calibration of analytical instruments (HPLC, LC-MS) for the accurate detection and quantification of mycotoxin contamination in grains, food, and feed.
• Biochemical Studies: Serves as a potent tool to investigate eukaryotic protein synthesis inhibition and study ribosome function in cell biology research.
• Method Development & Validation: Essential for developing, validating, and ensuring the compliance of analytical methods in accordance with international guidelines.
• Academic Research: Used in university and institutional labs for fundamental studies on fungal metabolites, natural product chemistry, and environmental toxicology.
• Quality Control & Assurance: Acts as a certified reference material (CRM) for the internal quality control of laboratories testing for mycotoxin presence.

Basic Information

Product Name	Verrucarin L
CAS No.	77101-87-2
Molecular Formula	C₂₇H₃₄O₉
Molecular Weight	502.56 g/mol
Synonyms	Verrucarin L; 12,13-Epoxytrichothec-9-ene-4,15-diol, 3-acetate 15-(3-methyl-2-butenoate), (3α,4β,15-acetoxy-12,13-epoxytrichothec-9-en-3,4,15-triol 3-acetate 15-angelate?; Roridin L-2; Trichothec-9-ene-3,4,15-triol, 12,13-epoxy-, 3-acetate 15-(3-methyl-2-butenoate), (3α,4β,15α)-; Antibiotic LL-S88β; LL-S 88β; Antibiotic S 88β
EINECS	Contact for details

Quality Control

Our Verrucarin L is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation. A detailed Certificate of Analysis (COA) containing lot-specific data is provided with every shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation. The material should be stored in a cool, dry, and well-ventilated area dedicated for research chemicals.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.