Description

(1Ar,4E,7R,7Ar,10As,10Br)-1A,2,3,6,7,7A,8,9,10A,10B-Decahydro-7-[[(Z)-2-Methyl-2-Butenoyl]Oxy]-1A,5-Dimethyl-8-Methyleneoxireno[9,10]Cyclodeca[1,2-B]Furan-9-One is a high-purity, complex sesquiterpene lactone derivative, valued for its intricate molecular architecture and specific biological activity. This compound is critical for advanced research and development in pharmaceutical chemistry, serving as a sophisticated intermediate or reference standard. It is primarily sought by R&D teams in the pharmaceutical, agrochemical, and fine chemical sectors for the synthesis of novel active ingredients and for structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential therapeutic agents, particularly in oncology and anti-inflammatory drug discovery.
• Biochemical Research: Used as a reference standard or probe in pharmacological studies to investigate biological pathways and enzyme interactions.
• Agrochemical Development: Acts as a precursor or model compound for creating new crop protection agents with specific modes of action.
• Fine Chemical Synthesis: Employed in complex multi-step organic syntheses requiring high stereochemical control and specific functional groups.
• Academic Research: Utilized in university and institutional labs for methodological development in total synthesis and natural product chemistry.

Basic Information

Product Name	(1Ar,4E,7R,7Ar,10As,10Br)-1A,2,3,6,7,7A,8,9,10A,10B-Decahydro-7-[[(Z)-2-Methyl-2-Butenoyl]Oxy]-1A,5-Dimethyl-8-Methyleneoxireno[9,10]Cyclodeca[1,2-B]Furan-9-One
CAS No.	77096-83-4
Molecular Formula	C20H26O5
Molecular Weight	346.42 g/mol
Synonyms	7α-(2-Methyl-2-butenoyloxy)-1a,5-dimethyl-8-methylenexo-oxireno[9,10]cyclodeca[1,2-b]furan-9-one; Parthenolide derivative; Sesquiterpene lactone ester; 7-Tigloyloxyparthenolide analog; (Z)-Tiglate ester of a parthenolide derivative; Oxireno[9,10]cyclodeca[1,2-b]furan-9-one derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of this advanced chemical intermediate is produced and verified under a strict quality management system. We employ state-of-the-art analytical techniques, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.