Description

24(S),25-Epoxycholesterol (Not Deuterated) is a specific, non-deuterated stereoisomer of an oxysterol, a class of oxidized derivatives of cholesterol. This compound is a critical biochemical tool for researchers investigating cholesterol biosynthesis, metabolism, and the regulatory roles of oxysterols in cellular signaling pathways. It is primarily utilized in pharmaceutical R&D, academic biochemistry, and life science laboratories focused on lipid biology and metabolic disease research.

Application

• Biochemical Research: Used as a reference standard and analytical reagent in studies of cholesterol biosynthesis and metabolism.
• Cell Signaling Studies: Investigated for its role as a potential ligand or modulator in nuclear receptor (e.g., LXR) and other signaling pathways.
• Pharmaceutical Development: Serves as a key intermediate or reference compound in drug discovery programs targeting cholesterol-related disorders.
• Metabolic Pathway Analysis: Employed in enzymatic assays and metabolic flux studies to elucidate the 24(S),25-epoxycholesterol pathway.
• Academic & Institutional Research: Essential for universities and research institutes conducting fundamental research in lipidology and sterol chemistry.

Basic Information

Product Name	24(S),25-Epoxycholesterol (Not Deuterated)
CAS No.	77058-74-3
Molecular Formula	C27H44O2
Molecular Weight	400.64 g/mol
Synonyms	(24S)-24,25-Epoxycholesterol; 24(S),25-Epoxycholesterol; 24S,25-Epoxycholesterol; (24S)-24,25-Epoxy-5-cholesten-3β-ol; 5-Cholesten-3β-ol, 24,25-epoxy-, (24S)-; 24(S)-Epoxycholesterol
EINECS	Contact for details

Quality Control

Our 24(S),25-Epoxycholesterol (Not Deuterated) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Specific Rotation	Contact for details
Solubility	Soluble in DMSO, ethanol, chloroform

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.