Description

(3R)-3-(4-Hydroxybenzyl)-1,4-Dimethyl-3β,6β-Bis(Methylthio)-2,5-Piperazinedione is a specialized, high-purity synthetic intermediate belonging to the class of substituted piperazinediones. This compound is valued for its unique stereochemistry and functional groups, which make it a critical building block in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic pathways.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its unique heterocyclic structure for biological activity.
• Fine Chemical Synthesis: Acts as a versatile building block for creating specialized ligands, catalysts, and other high-value organic molecules.
• Academic & Institutional R&D: Employed in university and government laboratories for methodological studies in asymmetric synthesis and heterocyclic chemistry.
• Peptidomimetic Development: Its piperazinedione core is useful in designing peptide analogs and conformationally restricted scaffolds for medicinal chemistry.

Basic Information

Product Name	(3R)-3-(4-Hydroxybenzyl)-1,4-Dimethyl-3β,6β-Bis(Methylthio)-2,5-Piperazinedione
CAS No.	77053-26-0
Molecular Formula	C16H22N2O3S2
Molecular Weight	354.49 g/mol
Synonyms	(3R)-3-(4-Hydroxybenzyl)-1,4-dimethyl-3,6-bis(methylthio)piperazine-2,5-dione; 3β,6β-Bis(methylthio)-3-(4-hydroxybenzyl)-1,4-dimethyl-2,5-piperazinedione; (3R)-3-(4-Hydroxybenzyl)-1,4-dimethyl-3,6-bis(methylsulfanyl)piperazine-2,5-dione; 77053-26-0; L-77053-26-0; Substituted Piperazinedione Derivative; Bis-methylthio piperazinedione intermediate
EINECS	Contact for details

Quality Control

Our (3R)-3-(4-Hydroxybenzyl)-1,4-Dimethyl-3β,6β-Bis(Methylthio)-2,5-Piperazinedione is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and isomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.