Description

2-[2-[4-[(4-Chlorophenyl)Benzyl]Piperazin-1-Yl]Ethoxy]Ethyl 2-(3-Benzoylphenyl)Propionate, Bis(Sulphate) is a high-purity, complex organic salt with significant pharmacological potential. This compound is valued for its precise chemical structure, which serves as a critical intermediate in advanced pharmaceutical synthesis. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within central nervous system (CNS) and anti-inflammatory drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of proprietary active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Preclinical Development: Serves as a critical material for pharmacokinetic, pharmacodynamic, and toxicology studies.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in API manufacturing.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-[2-[4-[(4-Chlorophenyl)Benzyl]Piperazin-1-Yl]Ethoxy]Ethyl 2-(3-Benzoylphenyl)Propionate, Bis(Sulphate)
CAS No.	76860-22-5
Molecular Formula	C37H39ClN2O9S2
Molecular Weight	755.30 g/mol
Synonyms	2-[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]ethyl 2-(3-benzoylphenyl)propanoate bis(hydrogen sulfate); Loxoprofen piperazine salt derivative; 2-(3-Benzoylphenyl)propionic acid 2-[2-[4-[(4-chlorophenyl)benzyl]piperazin-1-yl]ethoxy]ethyl ester bis(sulfate); Loxoprofen-related compound; [2-[2-[4-[(4-Chlorophenyl)-phenylmethyl]-1-piperazinyl]ethoxy]ethyl 2-(3-benzoylphenyl)propanoate sulfate (1:2)
EINECS	Contact for details

Quality Control

Our 2-[2-[4-[(4-Chlorophenyl)Benzyl]Piperazin-1-Yl]Ethoxy]Ethyl 2-(3-Benzoylphenyl)Propionate, Bis(Sulphate) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.