Description

Dl-2-Amino-5-Phosphonopentanoic Acid CAS NO 76726-92-6 is a phosphonic acid derivative of glutamic acid, functioning as a competitive NMDA receptor antagonist. This compound is a critical research-grade biochemical for investigating excitatory amino acid neurotransmission and neuropharmacology. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers focused on neuroscience and receptor studies.

Application

• Neuroscience Research: A standard tool for studying NMDA receptor function, synaptic plasticity, and excitotoxicity in cellular and animal models.
• Pharmacological Studies: Used to characterize and validate the role of glutamatergic pathways in various neurological conditions.
• Biochemical Assay Development: Serves as a reference standard and active control in high-throughput screening (HTS) assays for drug discovery targeting neurological disorders.
• Academic & Industrial R&D: Fundamental reagent for basic research in neurochemistry and for developing novel therapeutic agents.
• Chemical Synthesis: Acts as a key chiral building block or intermediate for the synthesis of more complex neuroactive compounds and analogs.

Basic Information

Product Name	Dl-2-Amino-5-Phosphonopentanoic Acid
CAS No.	76726-92-6
Molecular Formula	C5H12NO5P
Molecular Weight	197.13 g/mol
Synonyms	DL-AP5; DL-2-Amino-5-phosphonovaleric acid; DL-APV; (±)-2-Amino-5-phosphonopentanoic acid; (RS)-2-Amino-5-phosphonopentanoic acid; DL-2-Amino-5-phosphono-valeric acid; NMDA receptor antagonist AP5; Phosphonic acid, P-[(1RS)-1-amino-4-carboxybutyl]-
EINECS	Contact for details

Quality Control

Our Dl-2-Amino-5-Phosphonopentanoic Acid is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.