Description

Butanoic Acid, 2-Methyl-3-Oxo-, (R)- (9Ci) is a chiral, optically active organic compound belonging to the class of keto acids. This specific enantiomer is of significant interest in advanced organic synthesis and pharmaceutical research, where stereochemical purity is critical for biological activity and process development. It serves as a valuable chiral building block or intermediate for researchers and manufacturers in the fine chemical, agrochemical, and active pharmaceutical ingredient (API) sectors.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where the specific stereochemistry can influence efficacy and environmental impact.
• Fine Chemical Production: Acts as a precursor for flavors, fragrances, and other specialty chemicals requiring high stereoselectivity.
• Biochemical Research: Employed in enzymatic studies and as a standard for analytical method development in chiral separation techniques (e.g., HPLC, GC).
• Asymmetric Catalysis: Serves as a ligand precursor or a test substrate in the development of new asymmetric synthetic methodologies.

Basic Information

Product Name	Butanoic Acid, 2-Methyl-3-Oxo-, (R)- (9Ci)
CAS No.	76652-86-3
Molecular Formula	C5H8O3
Molecular Weight	116.12 g/mol
Synonyms	(R)-2-Methyl-3-oxobutanoic acid; (R)-3-Oxo-2-methylbutyric acid; D-2-Methylacetoacetic acid; (R)-2-Methyl-3-oxobutyric acid; (R)-3-Keto-2-methylbutanoic acid; (2R)-2-Methyl-3-oxobutanoic acid; (R)-Methylacetoacetate (acid form)
EINECS	Contact for details

Quality Control

Our production of (R)-2-Methyl-3-oxobutanoic acid adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and enantiomeric excess (e.e.) meet exacting standards. Comprehensive analytical control, including chiral HPLC, NMR, and specific rotation measurement, is employed. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% e.e.
Specific Rotation [α]	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.