Description

4-Aminopiperidine-4-Carboxylic Acid Hydrobromide is a high-purity, pharmaceutically relevant building block and salt form of a constrained amino acid derivative. This compound is a critical intermediate in the synthesis of complex molecules, offering a unique scaffold for medicinal chemistry and drug discovery programs. It is primarily utilized by research institutions and pharmaceutical companies developing novel therapeutic agents, particularly in areas requiring sophisticated peptidomimetics and bioactive heterocycles.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Peptidomimetic Research: Serves as a constrained, functionalized amino acid analog in the design of peptide-like molecules with enhanced metabolic stability and bioavailability.
• Medicinal Chemistry Scaffold: Used to construct diverse heterocyclic libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Chemical Biology Probes: Employed in the development of tool compounds and probes to study biological pathways and enzyme functions.
• Salt Formation Studies: The hydrobromide salt form is utilized to improve the physicochemical properties, such as crystallinity and solubility, of lead compounds.

Basic Information

Product Name	4-Aminopiperidine-4-Carboxylic Acid Hydrobromide
CAS No.	76508-55-9
Molecular Formula	C6H13N2O2 • HBr
Molecular Weight	225.10 g/mol
Synonyms	4-Amino-4-piperidinecarboxylic acid hydrobromide; 4-Aminoisonipecotic acid hydrobromide; 4-Aminopiperidine-4-carboxylic acid HBr; 4-Carboxy-4-aminopiperidine hydrobromide; 4-Piperidinecarboxylic acid, 4-amino-, hydrobromide (1:1); 4-Amino-4-carboxypiperidine hydrobromide; 4-Aminopiperidine-4-carboxylic acid monohydrobromide
EINECS	Contact for details

Quality Control

Our 4-Aminopiperidine-4-Carboxylic Acid Hydrobromide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.