Description

Ligustrazine Hydrochloride is a high-purity pharmaceutical intermediate and active ingredient derived from the traditional Chinese herb *Ligusticum chuanxiong* Hort. This compound matters for its significant role in cardiovascular and cerebrovascular research, offering potential therapeutic benefits. It is primarily needed by pharmaceutical manufacturers, R&D laboratories, and nutraceutical companies focused on developing treatments for improving microcirculation and managing ischemic conditions.

Application

• Pharmaceutical Active Ingredient: Used in the formulation of injectable and oral medications targeting cardiovascular and cerebrovascular diseases.
• Research & Development: A key reference standard and intermediate in pharmacological studies for its vasodilatory and anti-platelet aggregation properties.
• Nutraceutical Supplements: Incorporated into dietary supplements aimed at supporting healthy blood flow and circulation.
• Traditional Medicine Modernization: Serves as a standardized extract component in modernized herbal preparations.
• Biochemical Reagent: Utilized in laboratory settings for cell culture studies and biochemical pathway analysis related to ischemia-reperfusion injury.

Basic Information

Product Name	Ligustrazine Hydrochloride
CAS No.	76494-51-4
Molecular Formula	C8H12N2·HCl
Molecular Weight	172.65 g/mol
Synonyms	Chuanxiongzine Hydrochloride; Tetramethylpyrazine Hydrochloride; 2,3,5,6-Tetramethylpyrazine Hydrochloride; Ligustrazine HCl; TMPZ HCl;川芎嗪盐酸盐; Pyrazine, tetramethyl-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our Ligustrazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade standards suitable for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.