Description

Bicyclo[2.2.1]Heptane, 2-Bromo-, (1R-Endo)- (9Ci) is a high-purity, chiral brominated norbornane derivative, serving as a critical chiral building block and ligand precursor in advanced organic synthesis. Its rigid, three-dimensional bicyclic framework and defined stereochemistry make it invaluable for constructing complex molecular architectures with precise spatial orientation. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty materials industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery.
• Agrochemical Research: Used in developing chiral pesticides and herbicides, where the specific stereochemistry can influence biological activity and environmental degradation.
• Ligand & Catalyst Development: Serves as a precursor for chiral phosphine and N-heterocyclic carbene (NHC) ligands used in asymmetric catalysis (e.g., hydrogenation, cross-coupling).
• Material Science: A monomer or cross-linking agent for synthesizing polymers with unique thermal and mechanical properties due to its rigid norbornane core.
• Organic Synthesis Building Block: Employed in Diels-Alder reactions, nucleophilic substitutions, and cross-coupling reactions to introduce sterically hindered, chiral motifs.
• Academic & R&D: A valuable reagent for methodological studies in stereoselective synthesis and mechanistic investigations.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane, 2-Bromo-, (1R-Endo)- (9Ci)
CAS No.	76420-01-4
Molecular Formula	C7H11Br
Molecular Weight	175.07 g/mol
Synonyms	(1R-endo)-2-Bromonorbornane; endo-2-Bromonorbornane; 2-Bromobicyclo[2.2.1]heptane (endo-); (1R,2S,4R)-2-Bromobicyclo[2.2.1]heptane; Bicyclo[2.2.1]heptane, 2-bromo-, (1R-endo)-; 2-Bromo-endo-norbornane; endo-2-Bromobicyclo[2.2.1]heptane
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptane, 2-Bromo-, (1R-Endo)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 99.0% ee (endo isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.